Ultra fast oscillations in the human brain and their functional significance

• Autoři: BRÁZDIL Milan; TRÁVNÍČEK Vojtěch; CUROT Jonathan; PAIL Martin; SŁUŻEWSKA-NIEDŹWIEDŹ Monika; ROMAN Robert; BARBEAU Filip PlešingerEmmanuel; KUCEWICZ Michal; KLIMEŠ Petr; CIMBÁLNÍK Jan; JURÁK Pavel; STACEY William C; WORRELL Gregory A
• Rok publikování: 2025
• Druh: Článek v odborném periodiku (nerecenzovaný)
• Fakulta / Pracoviště MU: Lékařská fakulta
• Popis: Human brain cell assemblies fire electrical impulses up to very high frequencies, which limit is not yet known. Using advanced intracranial microEEG recordings in a cohort of epileptic patients, we newly identified short-lasting oscillations in frequencies between 2 and 8 kHz. These ultra fast oscillations were consistently and locally detected in epileptic hippocampi but were extremely rare in non-epileptic brain tissue. The discovered electrophysiological phenomena thus may reflect neuronal hyperexcitability.

Související projekty

• Národní ústav pro neurologický výzkum