Microwave Application in 1,3-Dipolar Cycloadditions and Their Influence upon Formation of either 1,3-Oxazolidines or Pyrrolidines
| Autoři | |
|---|---|
| Rok publikování | 2000 |
| Druh | Článek ve sborníku |
| Konference | Proceedings - International Conference on Microwave Chemistry |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Organická chemie |
| Popis | A way to preparation of ethyl-N-alkyl-3,4-disubstituted pyrrolidine-2-carboxylates by the reaction of azomethine ylide and dipolarophile under microwave irradiation was searched. The ylide was generated in situ by the reaction of ethyl-N-alkylaminoacetates with paraformaldehyde. Fumaronitrile and dimethylfumarate were used as dipolarophiles. Comparison of reaction in toluene and under solventless conditions as well as influence of a solid support was searched. |
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